Applied Mathematician & Mathematical Biologist

Sarafa A. Iyaniwura

Research Scientist
Vaccine & Immunology Statistical Center,
Vaccine and Infectious Disease Division,
Fred Hutchinson Cancer Center, Seattle, WA.

A Brownian particle on a reflecting disk, hunted by a rotating absorbing trap.

About

Portrait of Sarafa Iyaniwura

I am an Associate Research Scientist in Hyrien Lab, and also a member of the Vaccine & Immunology Statistical Center (VISC), in the Biostatistics, Bioinformatics and Epidemiology (BBE) Program, of the Vaccine and Infectious Disease Division (VIDD) at Fred Hutchinson Cancer Center. I am an MGB-SIAM Early Career Fellow.

Prior to this, I was a Post-doctoral Research Associate at the Theoretical Biology and Biophysics group of the Los Alamos National Laboratory, New Mexico, USA, working with Alan S. Perelson, Ruy M. Ribeiro, and Ruian Ke. I obtained my Ph.D. from the Department of Mathematics and the Institute of Applied Mathematics (IAM) of the University of British Columbia (UBC), Vancouver, working with Michael Ward, Colin Macdonald, and Daniel Coombs.

Before my studies at UBC, I obtained a Masters degree in Mathematical Sciences from Stellenbosch University, South Africa, through the fully funded scholarship program offered by the African Institute for Mathematical Sciences (AIMS), Cape Town, South Africa.

Research

I am interested in developing mathematical modeling and analytical frameworks for analyzing biological systems. My current research at Fred Hutch focuses on developing data-driven mathematical modelling frameworks for understanding B-cell dynamics during vaccine-induced immune response, and using the framework to optimize gremline-targeting and sequential immunization strategies in the context of HIV vaccine. The techniques developed in this research will be applied to design vaccine regimens and improve clinical trial outcome, thereby reducing the time and cost for developing and effective vaccine for HIV.

I am also interested in other aspects of infectious disease modeling both within a host and at the population level, and modeling immune response to infections. Furthermore, I am interested in developing and analyzing reaction-diffusion systems, and developing theoretical framework for analyzing first passage time theory for passive and active Brownian systems.

I use ordinary differential equations (ODEs), partial differential equations (PDEs), agent-based models, and statistical and machine-learning models. To analyze the ODE and PDE models, I employ analytical techniques such as dynamical systems theory, perturbation theory, asymptotic analysis, and biophysical methods, and solve them numerically using finite difference, finite element, and closest point methods.

Teaching

Math 215/255: Elementary Differential Equations I

Topics: First-order equations, linear equations, linear systems, Laplace transforms, numerical methods, trajectory analysis of plane nonlinear systems. Applications of these topics will be emphasized.

  • Section 104, Fall 2017
  • Lectures: 1:00 - 2:00 pm Monday, Wednesday, and Friday
  • Venue: Irving K Barber Learning Centre, Room 261
  • Office hours: LSK 300, Mondays 11am - 12noon and Wednesdays 11am - 12noon

Grants and Awards

  1. 2026

    HIV Vaccine Trials Network (HVTN) Travel Award

    Award to attend the 2026 HVTN Translational HIV Vaccine Early-Stage Investigator (ESI) Conference and NHP AIDS Symposium.

    San Antonio, Texas, U.S.A.

  2. 2026
  3. 2024

    The Life Sciences and Dynamical Systems Travel Award

    Award to attend the 2024 SIAM Conference on the Life Sciences (LS24)

    Portland, Oregon, U.S.A., June 10 - 13, 2024.

  4. 2024

    MGB-SIAM Early Career Fellow.

    Period: 2024 - 2026.

  5. 2020
  6. 2020S, 2020W, 2021S, 2021W
  7. 2019
  8. 2016 - 2020
  9. 2014 - 2018
  10. 2013

    African Institute for Mathematical Sciences (AIMS) Fully-funded Master's Scholarship for African Students, South Africa.

  11. 2012

    Best Graduating Student, Faculty of Sciences, University of Ilorin, Nigeria.

  12. 2012

    Best Graduating Student, Department of Mathematics, University of Ilorin, Nigeria.

  13. 2012

    Silver Award Winner, Annual Nigerian National Mathematics Competition for University Students (NAMCUS), National Mathematical Center (NMC), Nigeria.

  14. 2009 - 2012

    University Undergraduate Scholarship, University of Ilorin, Nigeria.

Some conferences, workshops, and other events I co-organized or participated in

  1. Mini-symposium: Mathematical Modeling and Immunological Perspectives on Infectious Diseases (Parts I - III)

    SIAM Conference on the Life Sciences 2026

    Date: July 5 – 9, 2026.

    Venue: Huntington Convention Center of Cleveland, Ohio, USA.

  2. Mini-symposium: First Passage Phenomena in Brownian and Active Matter

    Canadian Applied and Industrial Mathematics Society Annual Meeting 2026

    Date: Jun 15 – 19, 2026.

    Venue: University of Regina, Saskatchewan, Canada.

  3. Mathematical modelling for model-informed drug development and virtual clinical trial (MMAVCT 2023)

    Career & Innovation Hub

    Date: May 1-2, 2023

    Venue: Virtual

  4. UBC Math-Bio Fall 2021 Welcome back event

    Date: Wednesdays, 15 September 2021 at 2:00 - 3:00 PM

    Venue: Virtual

  5. Panel member: Equality, Diversity and Inclusion in Mathematics: An open discussion of Equality, Diversity and Inclusion in Mathematics

    CAIMS/SCMAI Annual Meeting 2021

    Date: June 23, 2021

    Venue: Virtual

  6. Chair for contributed talks 4 session for CDEV-CT04: CDEV (Cell and Developmental Biology) Subgroup

    Society for Mathematical Biology conference, SMB2021

    Date: June 15, 2021

    Venue: Virtual

  7. Frontiers in Biophysic Conference 2021

    Date: June 28 - 29, 2021

    Venue: Virtual

  8. UBC weekly Math-Bio Seminar: April 2021 to October 2021

    Date: Wednesdays at 2:05 PM - 3:05 PM

    Venue: Virtual

  9. Frontiers in Biophysic Conference 2020 (Postponed to next year)

    Venue: TBA.

  10. Twelfth Annual Institute of Applied Mathematics (IAM), UBC Retreat 2016

    Venue: Corrigan nature house, 2645 Dollarton Highway, North Vancouver, BC V7H 1B1.